an709-determination of loss on drying by tga according

Application of Thermogravimetric Analysis for the

loss in an atmosphere within a specific temperature range provides the compositional analysis The deter-mination of the ash content is found after the gas switchover from nitrogen to air when either of the following takes place: 1 A mass loss plateau is established in the range of 600–950C or 2 the first

MOISTURE CONTENT BY THE OVEN

Douglas-fir western red cedar and western juniper According to ASTM D4442 oven drying can drive volatile compounds out of some species of wood When this occurs the wood weighs less than if just the water had been removed When the moisture content is calculated the value is too high

DRYING

Drying has a number of close synonyms Dehydration is the process of depriving a material of its water or the loss of water as a constituent The term is often used in food-drying operations to describe processes which strive to expel moisture but retain other volatile constituents in the original material and which are responsible for valuable aromatic and flavoring properties

SOP on Operation Calibration Cleaning and Maintenance of

Set required temperature (250 0C for depyrogenation and 100 0C for drying) using COURSE and FINE temperature adjustment knobs Rotate the arrow mark of energy regulator knob from OFF position to LOW MEDIUM or HIGH position according to the temperature requirement and urgency to reach the required temperature

TEST METHODS OF RUBBER MATERIALS AND PRODUCTS

constant shows higher portion of aromates in oil It can be figured out in according to the relation: 0 718 ( 0 276) 0 1 (log log( 0 8)) VHK ρ15 − − η50 + = Where: ρ15 is density at 15 C in g/cm 3 η50 is cinematic viscosity at 50 C in mm 2/sec

REVISION OF MONOGRAPH ON TABLETS

residual moisture after the drying step is important for smooth tablet compression Too low or too high moisture contents may influence the chemical and physical stability of the final tablet The granulate and powders normally need to be mixed with glidants and lubricants before the compression stage to

REVISION OF MONOGRAPH ON TABLETS

residual moisture after the drying step is important for smooth tablet compression Too low or too high moisture contents may influence the chemical and physical stability of the final tablet The granulate and powders normally need to be mixed with glidants and lubricants before the compression stage to

WHO List of Prequalified Quality Control Laboratories

Laboratories are listed according to WHO regions and within the region in the alphabetical order Kindly ensure that the most pH loss on drying water content density melting point FTIR HPLC (UV-VIS detection) TGA) IR TLC HPLC spectrophotometry and basic

PERKINELMER TGA 4000 INSTALLATION AND HARDWARE

38 TGA 4000 Installation and Hardware Guide Set Up the TGA 4000 System Components Place the TGA 4000 on your laboratory bench Do not plug in the power cord until instructed The computer and printer should already be on the bench and installed according to each item's instructions Page 39 Install a TGA 4000 39 1 Remove the fuse holder

GENERAL GUIDANCE FOR INSPECTORS ON "HOLD

Loss on drying Water content Particle size distribution Bulk density Tap density Angle of repose Blend Microbial test Moisture content Blend uniformity Particle size Bulk/tapped density Core tablets – uncoated (In bulk containers) Description Hardness Thickness Friability Appearance 2 These parameters are examples Manufacturers have to

Magnesium citrate

Loss on drying (1 000 g dried in an oven for 5 h at 18010C: Ph Eur method 2 2 32 and 8 mL of distilled water R and adding 0 2 mL of dilute ammonia solution R and adjusting the pH to 3 6 (according to Ph Eur method 2 2 3) Make up to a volume of 15 mL Key to abbreviations The Therapeutic Goods Administration is part of the Health

LABSYS evo

LABSYS evo TGA sensor is an alumina based rod held by the balance and equipped with a sample temperature measurement thermocouple The sample is held in an alumina (440 μL) or platinum (500 μL) crucible The state-of-the-art Calisto data treatment software allows for numerous automatic operations like blank subtraction for hassle free buoyancy effect correction DTG signal calculation for

2 9 40 UNIFORMITY OF DOSAGE UNITS

precautions to avoid uptake or loss of moisture Weigh the individual shells and calculate the net contents Calculate the active substance content on each capsule from the mass of product removed from the individual capsules and the result of the assay Calculate the acceptance value Solid dosage forms other than tablets and capsules

E1868

Calculation 12 1 Calculate percent mass loss according to the following equation: m5 ~mi – mf! 3 100 % mi (1) LOD 5 mean value of m for duplicate determinations where: 3 E 1868 – 02 LOD m mi mf = = = = loss-on-drying (%) percent mass loss (%) initial mass (mg) and ?nal mass (mg) performance standards were synthetic materials made up to

DETERMINATION OF MOISTURE AND TOTAL SOLIDS

Drying foods in a vacuum oven therefore has a number of advantages over conventional oven drying techniques If the sample is heated at the same temperature drying can be carried out much quicker Alternatively lower temperatures can be used to remove the moisture ( e g 70 o C instead of 100 o C) and so problems associated with degradation

Determination of Volatiles in Pharmaceutical Certified

The loss on drying (LOD) technique is largely used in pharmaceutical laboratories to determine the total amount of volatiles i e water and residual solvents 9 29 32 vaporized under the experimental conditions The test is quite simple 3 29 and depends only on a properly calibrated analytical balance and

Loss on Drying / Loss on Ignition

Custom designed products can also incorporate an integrated balance for loss on drying loss on ignition and thermogravimetric analysis One example illustrated on the right is a custom-built retort furnace up to 900C for 250kg loads which includes a balance with 5g accuracy and measures mass loss under inert gas atmosphere

GENERAL GUIDANCE FOR INSPECTORS ON "HOLD

Loss on drying Water content Particle size distribution Bulk density Tap density Angle of repose Blend Microbial test Moisture content Blend uniformity Particle size Bulk/tapped density Core tablets – uncoated (In bulk containers) Description Hardness Thickness Friability Appearance 2 These parameters are examples Manufacturers have to

Thermogravimetric method validation and study of

TGA-FTIR Method: TGA was performed on a Mettler Toledo TGA/SDTA 851e module Samples were placed in open alumina pans for the TG experiments The typical sample size was 10-15 mg for TGA Temperature range was 30-400 C with a heating rate of 10 C/min Samples were purged by a stream of nitrogen flowing at 80 mL/min

MANUAL OF METHODS OF ANALYSIS OF FOODS

W1 = Loss in gm of the material on drying W = Weight in gm of the material taken for test (Ref :- I S I Hand book of Food Analysis (Part XIII) – 1984 page 62) 4 0 Determination of Specific Gravity 4 1 Preparation of Sample Melt sample if necessary Filter through a filter paper to remove any impurities and the last traces of moisture

Near infrared spectroscopy of magnesium stearate hydrates

The mixture compositions determined from TGA mass loss on drying (LOD) measurements were found to be inaccurate PLS regression was applied to the TGA thermograms of the standard mixtures to generate more accurate reference values and this model was then applied to a set of validation samples

DETERMINATION OF MOISTURE AND TOTAL SOLIDS

Drying foods in a vacuum oven therefore has a number of advantages over conventional oven drying techniques If the sample is heated at the same temperature drying can be carried out much quicker Alternatively lower temperatures can be used to remove the moisture ( e g 70 o C instead of 100 o C) and so problems associated with degradation

Solids Drying: Basics and Applications

Apr 01 2014Freeze-drying is an extreme form of vacuum drying in which the water or other solvent is frozen and drying takes place by subliming the solid phase Freeze-drying is extensively used in two situations: (1) when high rates of decomposition occur during normal drying and (2) with substances that can be dried at higher temperatures and that are

US8338619B2

A method to obtain a new crystalline form of the Zoledronic acid characterized by its X-rays diffractogram as well as by its spatial atomic distribution in the red crystalline and its curves of thermal analysis There is also included a method to obtain this crystalline form which includes the synthesis of the corresponding acid and the pharmaceutical composition this crystalline form comprises

Difference Between Water (Moisture) Content and Loss on

Loss on Drying is an unspecific analytical technique removing not only water but all other volatile impurities like alcohol etc from a sample The degree of drying depends upon 1) Temperature 2) Drying time LOD or total moisture content analysis of Pharmaceutical products can include both bound (e g water of hydration) free water

Comparison of methodologies for moisture determination on

generally large According to Cecchi (2003) drying through infrared radiation is more eff ective that drying in oven and involves penetration of heat inside the sample shortening the drying period Th is method while exposing the samples to an increase in temperature does it for short periods only Th is